We sought insights from four experienced gastroenterologists to delve into the best positions for relieving oneself: Salina Lee, MD, an assistant professor of gastroenterology at Rush University in Chicago; Sophie M. Balzora, MD, a clinical professor of medicine at the New York University Grossman School of Medicine; Rohan Modi, MD, a member of Squatty Potty’s advisory council; and Peter Stanich, MD, an associate professor of gastroenterology, hepatology, and nutrition at the Ohio State University Wexner Medical Center.